What you need to know about:

Brachytherapy (General)

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Overview of

Brachytherapy (General)

in Thailand

Brachytherapy is a type of radiotherapy used in the treatment of different types of cancer and involves placing the source of radiation directly in or near the cancerous tumor. This allows treatment to be more precise and reduces the damage to the healthy tissue around the tumor. Brachytherapy may be a standalone treatment option or may be combined with other treatments, such as external radiotherapy or surgery.  Brachytherapy may be used in the treatment of a number of cancers, including:

-Prostate cancer

-Cervical cancer

-Endometrial cancer

-Lung cancer

-Soft tissue sarcoma

-Breast cancer

-Vaginal cancer

-Head and neck cancer

-Anal cancer

-Skin cancer

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Brachytherapy (General)

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Brachytherapy (General)

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Pros and cons of

Brachytherapy (General)

Pros

-Increases the effectiveness of treatment as radiation can be focused on the location to be treatment.

-Low risk of side effects as radiation source may be placed within the tumor or nearby, which minimizes damage to surrounding tissue.

-It is a minimally invasive procedure that does not require major surgery.

-It can be done on an out-patient basis.

-Treatment duration is short and approximately takes one to five days.

-Recovery is shorter than that of surgery. Patient may return to their normal activities quite soon after the procedure.

Cons

-You need a general or a spinal anaesthetic.

-With radioactive seeds, you need to avoid close contact with children or pregnant women for a couple of months after treatment.

-Bladder side effects may be more severe than with external beam radiotherapy.

How it works:

Brachytherapy (General)

Brachytherapy is divided into three methods: Permanent implantation In permanent implantation the radiation source is implanted into the tumor permanently. The radioactive material is typically placed by hand with the guidance of an imaging test, such as ultrasound or CT. You may feel pain during the placement of radioactive material, but you shouldn't feel any discomfort once it's in place. Your body will emit low doses of radiation from the area being treated at first. Usually the risk to others is minimal and may not require any restrictions about who can be near you. In some cases, for a short period of time you may be asked to limit the length and frequency of visits with pregnant women or with children. The amount of radiation in your body will diminish with time, and restrictions will be discontinued.The radiation source will be as small as a sesame seed and a very small amount of low-level radiation will be released slowly until the source is depleted. This type of brachytherapy is often used for the treatment of low risk localized prostate cancer. Low dose rate brachytherapy: During low-dose-rate brachytherapy, a continuous low dose of radiation is released over time — from several hours to several days. You'll typically stay in the hospital while the radiation is in place. Radioactive material is placed in your body by hand or by machine. Brachytherapy devices may be positioned during surgery, which may require anesthesia or sedation to help you remain still during the procedure and to reduce discomfort.You'll likely stay in a private room in the hospital during low-dose-rate brachytherapy. Because the radioactive material stays inside your body, there is a small chance it could harm other people. For this reason, visitors will be restricted.Children and pregnant women shouldn't visit you in the hospital. Others may visit briefly once a day or so. Your health care team will still give you the care you need, but may restrict the amount of time they spend in your room. You shouldn't feel pain during low-dose-rate brachytherapy. Keeping still and remaining in your hospital room for days may be uncomfortable. If you feel any discomfort, tell your health care team. After a designated amount of time, the radioactive material is removed from your body. Once brachytherapy treatment is complete, you're free to have visitors without restrictions. High-dose-rate brachytherapy: High-dose-rate brachytherapy is often an outpatient procedure, which means each treatment session is brief and doesn't require that you be admitted to the hospital. During high-dose-rate brachytherapy, radioactive material is placed in your body for a short period — from a few minutes up to 20 minutes. You may undergo one or two sessions a day over a number of days or weeks. You'll lie in a comfortable position during high-dose-rate brachytherapy. Your radiation therapy team will position the radiation device. This may be a simple tube or tubes placed inside a body cavity or small needles inserted into the tumor. The radioactive material is inserted into the brachytherapy device with the help of a computerized machine. Your radiation therapy team will leave the room during your brachytherapy session. They'll observe from a nearby room where they can see and hear you. You shouldn't feel any pain during brachytherapy, but if you feel uncomfortable or have any concerns, be sure to tell your caregivers.Once the radioactive material is removed from your body, you won't give off radiation or be radioactive. You aren't a danger to other people, and you can go on with your usual activities. The doctor will determine the most appropriate type of treatment for each patient by considering the following factors: -The location of the tumor -The size of the tumor -Risk classification for localized prostate cancer

Preparation before

Brachytherapy (General)

Pre - treatment

Before you begin brachytherapy, you may meet with a doctor who specializes in treating cancer with radiation (radiation oncologist). You may also undergo scans to help your doctor determine your treatment plan. Procedures such as X-rays, computerized tomography (CT) or magnetic resonance imaging (MRI) may be performed before brachytherapy.

Recovery after

Brachytherapy (General)

Post - treatment

You’ll need to stay in the hospital while undergoing HDR brachytherapy. Your body is radioactive during this time. If you have permanent brachytherapy you could potentially expose other people to radiation for several weeks or months. While the exposure risk is small, you should limit your contact with young children and pregnant women as directed by your doctor.

Risks & side effects

The side effects of brachytherapy vary and each patient may experience different side effects in different severities, depending on the location of cancer being treated, the stage of the disease, and other health complications. Thus, the patient undergoing brachytherapy should discuss possible side effects with their doctor and inform their doctor immediately when problems occur.  In general, side effects that occur just after your treatment are referred to as acute side effects. These generally disappear in a matter of weeks and are often related to the procedure itself or to the working of the radiotherapy. Long-term side effects usually occur in a small number of patients and are generally an effect of the radiation on adjacent tissues or organs. Studies have shown that patients in general suffer fewer side effects after brachytherapy in comparison to any other treatment. For more information, please refer to the specific cancer sections.

FAQs:

Brachytherapy (General)

How effective is brachytherapy in treating cancer?

Studies have shown that brachytherapy is comparable to external beam radiotherapy (EBRT) and surgery in the treatment of many kinds of cancer. In addition studies have also shown that patients often have fewer side effects after brachytherapy in comparison to other treatment options1 Results can improve even further when used in combination with these other treatments.

How long does brachytherapy treatment last?

The length of an individual’s brachytherapy treatment will depend on the type of cancer and treatment technique agreed between the patient and their healthcare team.  One of the recognized benefits of brachytherapy is the fact that patients typically spend very little time in hospital. Compared to other radiotherapy techniques, a course of high dose rate brachytherapy can be completed in less time (typically from 1-5 days) and patients typically have to make fewer visits to the radiotherapy clinic.  Many brachytherapy procedures are performed on an outpatient basis making it more convenient for patients, particularly for those who have to work, those with young families, older patients and those who live some distance from treatment centres. Brachytherapy patients also tend to benefit from quicker recovery times (typically 2 to 5 days).

How soon can I get back to work after brachytherapy?

After low dose rate brachytherapy, a couple of day's rest is usually recommended before going back to work. After high dose rate brachytherapy you may be able to return to work the following day.1

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