What you need to know about:

Electroporation (Electropermeabilization)

Fast Fact

88%
Worth It Rating
Average Cost:
$90
Recovery Period:
No downtime
Permanence:
Not specified
177
Doctors
Time it takes:
30 minutes - 1 hour
96
Hospitals & Clinics
Reviews
Anesthetize:
None

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Overview of

Electroporation (Electropermeabilization)

in Thailand

Electroporation is a technique used mainly to help introduce chemicals or treatments inside the cells by boosting the permeability of the cell membrane. This occurs through the introduction of high electrical energy which creates small channels on the cell membrane to allow the passage of the intended chemicals.

This was mainly used in microbiology and genetic studies. Electroporation clinical applications include cancer treatment, as well as gene therapy, and vaccine development.

Recently, dermatologists introduced the concept of electroporation in skin treatment (dermal electroporation) to intensify the effects of the chemical materials used such as hyaluronic acid, vitamin C serum, whitening serum, and other materials to solve some skin problems such as aging signs. This is called transdermal drug delivery which offers the advantage to deliver the drug without being metabolized as what happens in the oral route.

Electroporation is a safe painless way to create temporary pores in the cell membrane of the deeper skin layer through high voltage electric waves for a short time to increase the skin permeability and absorption of the applied nutrients or treatment to treat certain skin conditions or skin rejuvenation.

Studies have shown that electroporation helped introduce molecules to the deeper layers of skin 90%more than other conventional methods. It is a painless and less invasive technique when compared to the micro-needling method. Electroporation can create up to 500 more channels than that formed by the iontophoresis technique.

Goals of

Electroporation (Electropermeabilization)

The main problem facing dermatologists is the selective permeability characteristic of the skin owing to its stratum corneum layer which while provide protection to the body, prevents the passage of specific chemical composition compounds (large molecules and hydrophilic materials).

Electroporation was the key to increasing skin permeability and enhancing the absorption of the intended treatment materials through the introduction of high voltage electric energy for a short time (a few seconds). It is a safe, non-invasive, painless option to address multiple skin problems such as:

  • Aging signs and fine lines of expression.
  • Scaring as acne scarring post-surgical treatment scaring, and keloid scars.
  • Skin rejuvenation.
  • Skin firming (face, neck, breast).
  • Localized adiposity.
  • Hyper-pigmentation.
  • Cellulitis and stretch marks.
  • Melasma

Price of

Electroporation (Electropermeabilization)

in Thailand

Average Cost

$90

Price Range

$30 to $150

Pros and cons of

Electroporation (Electropermeabilization)

Pros

  • Allows better absorption and penetration of skin treatments to the deeper skin layers
  • Provide a passage for hydrophilic and lipophilic molecules which can’t be absorbed by regular passive absorption of the skin.
  • Restores skin balance, hydration, and nutrients stock which reflects by having a healthier and youthful appearance.
  • Showed good results when used to treat fine lines, wrinkles, and hyperpigmentation.
  • Long-lasting results.
  • Effective for all skin types, all cells, and all stages of the cell cycle.
  • Safe, painless, and non-invasive.

Cons

Although Electroporation is a safe technique, it may elicit temporary cell membrane damage by creating micro pores that may result in the death of a few cells, which only occurs when using an inappropriate electric current.

How it works:

Electroporation (Electropermeabilization)

  1. Your doctor will examine the skin to assess the problem and set the most suitable treatment plan.
  2. Before starting, your dermatologist will clean your face and apply the recommended treatment.
  3. The probe of the electroporation device is moved in a circular motion on your facial skin to allow better drug penetration and absorption by the deeper skin layers for about 30 minutes until complete absorption.
  4. Electroporation is recommended to be performed over 6-8 sessions once a week for higher efficacy results.

Preparation before

Electroporation (Electropermeabilization)

Pre - treatment

  1. Review of the medical history and history of any previous treatment concerning the area of interest.
  2. Examination of problem, skin type, and any related factor to determine the best treatment plan.
  3. Your dermatologist will discuss with you the treatment plan, explain the procedure step by step, and discuss all your concerns, treatment expectations, limitations, and your expectations.
  4. Do not attempt to do electroporation in case of active skin infection, allergy, atopic dermatitis, warts, photosensitivity, pregnancy, and dry irritated skin.

Recovery after

Electroporation (Electropermeabilization)

Post - treatment

Your dermatologist will give you some post-operative instructions to follow. That may include:

  1. Wait 3-4 hours before washing your face after the treatment.
  2. Avoid rubbing your face after treatment
  3. Use a mild facial cleaner during the treatment period
  4. Apply a moisturizer at least two times per day to provide skin hydration.
  5. Avoid direct sun exposure and use a broad-spectrum sunscreen.

Before and after photos of

Electroporation (Electropermeabilization)

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Patient reviews of

Electroporation (Electropermeabilization)

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BANGKOK-THAILAND - Verified Patients - 9 June 2021

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BANGKOK-THAILAND - Verified Patients - 9 June 2021

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Risks & side effects of

Electroporation (Electropermeabilization)

Skin electroporation is a safe painless technique that is suitable for all skin types. But few side effects may be seen due to improper adjustment of the electric current or overuse, such as itching or pricking sensation, few cell death, or skin dehydration due to water loss. These risks can be avoided by the correct use of the electric current, application time, and frequency according to the doctor’s recommendation.

FAQs:

Electroporation (Electropermeabilization)

How does electroporation work?

The electroporation technique involves the application of a high voltage electric pulse for a short time. This time is sufficient to open small channels or pores in the outer layer of the skin to allow the passage of specially formulated treatments or nutrients to help solve the addressed skin problem. Don’t worry these pores are not permanent, they close once the electroporation device is stopped.

 

Is Dermal Electroporation suitable for everyone?

Dermal Electroporation can be used for all skin types, but it is not indicated in the following medical conditions: epilepsy, pregnancy, breastfeeding, patients with bone implants, and cancer patients. Also, some local conditions may contraindicate the use of electroporation such as active skin infection, allergy, atopic dermatitis, warts, photosensitivity, and dry irritated skin.

What are the side effects of Electroporation?

Electroporation is non-invasive, painless, suitable for all skin types, and has no side effects unless unsuitable voltage is selected which may lead to itching and pricking sensation and sometimes cell death. These risks can be avoided by the correct use of the electric current, application time, and frequency according to the doctor’s recommendation.

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M.D
Kamthorn Siriphan
Cosmetic Dermatology
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